Nigel Scrutton, Director
Nigel Scrutton was appointed Director of the Manchester Institute of Biotechnology in September 2010. He is a Professor of Molecular Enzymology in the Faculty of Science and Engineering and an EPSRC Research Fellow. Nigel received a first class degree in Biochemistry from the University of London, King’s College (1985), and his PhD (1988) and ScD (2003) degrees from the University of Cambridge. At Cambridge he held a Royal Commission for the Exhibition of 1851 Research Fellowship (1988-91), College Research Fellowship (1989-92) and a Royal Society University Research Fellowship (1991-1999). In 1995 he moved to the University of Leicester as Royal Society University Research Fellow where he later became Lister Institute Research Professor of Biochemistry (1999-2004) and Professor of Biochemistry (1999-2005).
He was subsequently appointed Professor of Molecular Enzymology at the University of Manchester (2005), BBSRC Professorial Research Fellow (2006-2011) and Associate Dean for Research (2008). He is recipient of the Biochemical Society Colworth Medal, the Royal Society of Chemistry Chairman Medal, the RSC Rita and John Cornforth Award and a Royal Society Wolfson Research Merit Award.
Nigel has research interests in the mechanisms and structures of enzyme systems, with particular emphasis on understanding the physical basis of biological catalysis. His work is set at the interface of chemistry, biology and physics and is focused on elucidating fundamental mechanisms of enzyme systems from the quantum to macromolecular levels. His discoveries include new modes of enzymatic H-transfer by quantum mechanical tunneling mechanisms, conformational control of biological electron transfer reactions and the rational design/redesign of protein systems to catalyse new chemical transformations. A major current drive is to understand the nature of the coupling of dynamics to reaction chemistry. The group also has major interests in the application of enzymes in biotechnology.
Nick Turner, Deputy Director
Nick Turner is the Deputy Director of the Manchester Institute of Biotechnology. He is a Professor of Chemical Biology in the School of Chemistry and Director of the Centre for Biocatalysis, Biotransformations and Biocatalytic Manufacture (www.coebio3.org3). Nick obtained his DPhil in 1985 with Professor Sir Jack Baldwin and from 1985-1987 was a Royal Society Junior Research Fellow, spending time at Harvard University with Professor George Whitesides. He was appointed lecturer in 1987 at Exeter University and moved to Edinburgh in 1995, initially as a Reader and subsequently Professor in 1998. In October 2004 he joined Manchester University as Professor of Chemical Biology. He is also a co-founder and Scientific Director of Ingenza (www.ingenza.com), a spin-out biocatalysis company based in Edinburgh. He is a member of the Editorial Board of Chemical Communications.
Nick has research interests in the area of biocatalysis with particular emphasis on the discovery and development of novel enzyme catalysed reactions for applications in organic synthesis. His group are also interested in the application of directed evolution technologies for the development of biocatalysts with tailored functions.