MIB Bionanotechnology Facility
The Bionanotechnology facility includes instrumentation for the imaging, manipulation or measurement of single biomolecules or single molecule biochemical reactions.
Bionanotechnology techniques allow:
- Unbeatable sensitivity and specificity when detecting molecules and molecular interactions in solution or on a surface.
- Gathering of quantitative data on discrete systems for input into systems biology models.
- Identification of rare alternative reaction pathways and intermediates that are normally masked by ensemble averaging.
- Investigation of the mechanics of biological polymers and cell membranes.
Bionanotechnology equipment available in the facility includes:
- Multimode-Picoforce Atomic Force Microscope (AFM)
- JPK Cellhesion AFM (Michael Smith Building)
- Total Internal Reflection Fluourescence Microscope (TIRFM) [Available March 2011]
- Raman Laser Tweezers [Available Sep 2011]
- Fluorescence Correlation Spectrometer (FCS) [Available January 2012]