Enabling Technology

Enabling technologies represent the major driving force for quantitative bioscience. Accordingly, we pursue research and development of various types of technology and instrumentation in parallel with our research themes.

The primary thrust of our research in this area is measurement science, particularly the identification, quantitation, spatial or volume localisation.

Development

A key part of our work is the measurement of nano-scale molecular processes in biological systems.

In order to measure the desired parameters with the specificity and sensitivity required it is important that we understand the fundamental science of what we are trying to measure, and to be involved in the adaptation or development of instrumentation.

The systems being observed/measured/monitored range in size from small drug molecules, through proteins and DNA, to cells, small liquid droplets and biological tissue. Computational technology development is supporting activities in systems biology, text mining, molecular modelling, instrumentation control, and other areas across our research themes.
 
Major areas of activity include:

NMR, EPR

Mass spectrometry, Secondary ion mass spectrometry (SIMS)

Nanotechnology

Fast reaction techniques

Microfluidics

Separations science

IR spectroscopy

Computer software development

Integrative 'omic analysies and vitrational sepctroscopy for understanding biological systems

Single cell analysis within heterogeneous populations

Molecular imaging of cells and tissues

Predictive modelling of chemical structure and dynamics for drug design